Figure 5. Sequential 5‐AzadC + HDACI treatments induced a variation of cellular metabolic activity depending on the treatment in CD8⁺‐depleted PBMCs from HIV‐negative donors.

One night after cell purification, CD8⁺‐depleted PBMCs from 12 HIV‐negative donors were mock‐treated or treated with 5‐AzadC. Three days post‐treatment, 1/3 of medium was replaced and HDACIs were added to the cultures. Six days after 5‐AzadC treatment, WST‐1 assay was performed. Mock value was arbitrarily fixed at 100% for each individual. Means are indicated by a line.