Table 3.
Representation of reactivation status of ex vivo cultures of HLA DR− CD69− CD25− CD4+ T cells isolated from HIV+ patients
One night after cell purification, cells were mock‐treated or treated with 5‐AzadC. Three days post‐treatment, 1/3 of medium was removed and HDACIs were added in the cultures. Six days after 5‐AzadC treatment, the concentration of viral RNA in culture supernatants was determined (in copies/ml; ND means undetectable, and NA indicates an untested condition). Total HIV‐1 DNA is expressed as total HIV‐1 DNA copies/106 resting CD4+ T cells. The cultures highlighted in gray showed a higher viral production with the LRA combination than with the corresponding LRAs alone.