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. 2015 Dec 17;8(2):117–138. doi: 10.15252/emmm.201505557

Table 3.

Representation of reactivation status of ex vivo cultures of HLA DR CD69 CD25 CD4+ T cells isolated from HIV+ patients

graphic file with name EMMM-8-117-g013.jpg

One night after cell purification, cells were mock‐treated or treated with 5‐AzadC. Three days post‐treatment, 1/3 of medium was removed and HDACIs were added in the cultures. Six days after 5‐AzadC treatment, the concentration of viral RNA in culture supernatants was determined (in copies/ml; ND means undetectable, and NA indicates an untested condition). Total HIV‐1 DNA is expressed as total HIV‐1 DNA copies/106 resting CD4+ T cells. The cultures highlighted in gray showed a higher viral production with the LRA combination than with the corresponding LRAs alone.