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. 2016 Jan 29;18:35. doi: 10.1186/s13075-015-0805-0

Table 1.

Histological score criteria

Category Score Criteria
Inflammation 0 Normal
1 Minor infiltration of inflammatory cells at periphery of the joint
2 Moderate infiltration – inflammatory pannus < 50 % joint area
3 Marked infiltration – inflammatory pannus > 50 % joint area
Intervertebral disc destruction 0 Normal
1 Less than 50 % disc destruction
2 More than 50 % disc destruction
3 Total disc destruction/only necrotic disc left
Cartilage damage 0 Normal
1 Some loss of articular cartilage or growth plate cartilage or both
2 Severe loss of articular cartilage and some growth plate cartilage damage
3 Severe loss of articular cartilage and severe growth plate cartilage damage
Bone erosion 0 Normal
1 One or a few small areas of resorption in original vertebral bone.
2 Numerous areas of obvious focal resorption in original vertebral bone or several areas of severe destruction.
Excess tissue formation (excluding inflammatory infiltrate) 0 Normal
1 Mesenchymal cell invasion or expansion or both
2 Moderate fibrocartilage formation (<50 % of the original disc area)
3 Extensive fibrocartilage formation (>50 % of the original disc area)
Ectopic chondrocytes/chondrophyte 0 Normal
1 Single small area
2 Single large area
3 Multiple areas