Figure 1. Conceptual schematic of reward representations deficits in schizophrenia (SCZ). This figure outlines a conceptual overview of several processes thought to be involved in translating reward information into goal-directed behaviors, which may be compromised in SCZ and major depression (MD). The specific aspects of reward processing involve: (a) basic reward processing or “liking”; (b) reward-related learning and “wanting”; (c) reward information integration; (d) effort computation; and (e) reward representations over time. Breakdowns in the underlying computations across one or more of these processes may be involved in SCZ or MD. GABA, γ-aminobutyric acid; OFC, orbitofrontal cortex; ACC, anterior cingulate cortex; DLPFC, dorsolateral prefrontal cortex. Adapted from ref 176: Anticevic A, Dowd EC, Barch DM. Cognitive and motivational neuroscience of psychotic disorders. In: Charney D, Nestler EJ, Sklar P, Buxbaum J, eds. Neurobiology of Mental Illness. 4th ed. Oxford, UK: Oxford University Press; 2014. Copyright © Oxford University Press 2014.