Table 3.
Drugs involved in preventable and unpreventable adverse drug events according to the anatomical therapeutic and chemical (ATC) classification (one ADE can be due to more than one drug)
| Drugs classification according to ATC classification system | Preventable ADE [n (%)] | Unpreventable ADE [n (%)] | All ADE |
|---|---|---|---|
| Antineoplastic and immunomodulating agents | 3 (3 %) | 41 (41 %) | 44 (20 %) |
| Cardiovascular system | 36 (30 %) | 8 (8 %) | 44 (20 %) |
| Blood and blood-forming organs | 20 (17 %) | 23 (23 %) | 43 (20 %) |
| Nervous system | 30 (25 %) | 13 (13 %) | 43 (20 %) |
| Systemic hormonal preparation (except sex hormones and insulin) | 9 (8 %) | 7 (7 %) | 16 (7 %) |
| Anti-infective for systemic use | 7 (6 %) | 5 (5 %) | 12 (5 %) |
| Alimentary tract and metabolism | 4 (3 %) | 2 (2 %) | 6 (3 %) |
| Musculoskeletal system | 6 (5 %) | 0 (0 %) | 6 (3 %) |
| Others | 4 (3 %) | 1 (1 %) | 5 (2 %) |
| Total | 119 (100 %) | 100 (100 %) | 219 (100 %) |
The distribution of ATC classes implied in preventable and unpreventable ADE was compared: P = 2.2 × 10−13