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. 2015 Feb 20;26(7):1305–1313. doi: 10.1093/annonc/mdv076

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© The Author 2015. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved. For permissions, please email: journals.permissions@oup.com.

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Figure 2. — (A) Overall survival in patients receiving any HD-MTX-based therapy versus therapies not containing HD-MTX; (B) overall survival in patients receiving any HD-MTX + other chemotherapy versus HD-MTX monotherapy; (C) overall survival in patients receiving HD-MTX plus at least two other i.v. drugs (aggressive) versus HD-MTX plus oral chemotherapy; (D) overall survival in patients receiving HD-MTX-based chemotherapy with or without whole-brain radiotherapy. CTX, chemotherapy; HD-MTX, high-dose methotrexate; HR, hazard ratio.