Table 2.

sample size calculation scenarios

	Adherence score		Sample size needed*
	Control	Treat	Control	Treat	Total
LEAN Sample	0.72 (0.33)†	0.85 (0.33)	129	129	258‡
Non-adherent subgroup§	0.42 (0.35)	0.60 (0.35)	70	70	140

*Sample calculation assuming power of 0.85, significance level of 0.05 and a 10% dropout rate.

†SD in parentheses.

‡See the STATA codes for the sample calculation in the online supplementary appendix.

§Sample size of the baseline non-adherent subgroup achieved with a LEAN total sample of 258.