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. 2016 Jan 25;33(1):1–28. doi: 10.1007/s12325-015-0275-4

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© The Author(s) 2016

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 3 — MR perfusion images for a pathologically proven mixed oligoastrocytoma. Images a–d show baseline examination (a FLAIR; b T2-weighted pre-contrast; c T1-weighted post-gadopentetate dimeglumine; d dynamic susceptibility-weighted perfusion image with relative CBV color overlay map), which demonstrated a high baseline rCBV of 4.23, indicative of a high-grade tumor. Images e–h show the equivalent sequences at 18-week follow-up, and demonstrate substantial increase in tumor volume and a rCBV of 13.37 [100]. rCBV relative cerebral blood volume, FLAIR fluid-attenuated inversion recovery, MR magnetic resonance. Reproduced from Law et al. [100], Copyright 2014, with permission from The Radiological Society of North America (RSNA^®)