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Metal levels in bone and muscle of wild-type and flatiron mice. Metal levels were measured by ICP-MS in femurs (a) and quadriceps muscle (b). Empty and closed bars represent +/+ and ffe/+ mice, respectively. Data are mean ± SEM (n = 6 male and 4 female mice for each genotype). *P < 0.05 between +/+ versus ffe/+ mice; t test
