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. 2015 Sep 11;105:172–181. doi: 10.1007/s00392-015-0900-x

Table 3.

The value of traditional risk factors and clinical characteristics for predicting obstructive CAD

Variable Unadj. odds ratio (95 % CI) P value Adj. odds ratio (95 % CI) P Value
Traditional risk factors
 Age, per 5 years increase 1.13 (1.08–1.17) <0.001
 Male sex 2.50 (2.07–3.02) <0.001
 Diabetes 1.39 (1.16–1.66) <0.001
 Dyslipidemia 1.95 (1.64–2.31) <0.001
 Hypertension 1.11 (0.88–1.39) 0.389
 Former tobacco use 1.60 (1.32–1.93) <0.001
 Current tobacco use 1.86 (1.46–2.37) <0.001
Additional clinical characteristics
 Family history of CAD 1.06 (0.87–1.30) 0.553 1.19 (0.96–1.48) 0.118
 LV-EF <50 % 1.73 (1.37–2.19) <0.001 1.31 (1.02–1.69) 0.034
 hsCRP, per 5 mg/l 1.11 (1.06–1.17) <0.001 1.08 (1.03–1.14) 0.004
 Nt-proBNP, per 500 ng/l 1.11 (1.06–1.16) <0.001 1.06 (1.01–1.10) 0.009
Clinical presentation
 Nonanginal chest pain 0.69 (0.52–0.90) 0.007 0.85 (0.64–1.14) 0.290
 Atypical angina 1.07 (0.86–1.35) 0.543 1.38 (1.08–1.76) 0.011
 Typical angina 2.33 (1.86–2.91) <0.001 3.09 (2.42–3.95) <0.001
 Dyspnea NYHA II 0.83 (0.68–0.99) 0.042 0.90 (0.73–1.09) 0.274
 NYHA III 0.67 (0.50–0.90) 0.008 0.64 (0.46–0.88) <0.001