TableĀ 1.
Serological investigations, coagulation tests and genetic mutations affecting the alternate complement pathway and autoantibodies
ESR | 79 |
ANA | Negative |
ANCA | (MPO-11, PR3-3) |
Anti-GBM | Negative |
Cryoglobulins | Negative |
PT | Normal |
APPT | 43 |
Lupus anticoagulant | Negative |
Russell's viper venom test | Negative |
Mono test | Negative |
C3 | 0.87 |
C4 | 0.10 |
Surface regulation for alternate pathway | Normal |
Factor H autoantibody | Negative |
Soluble MAC level | Normal |
C3 nephritic factor | Negative |
Pathogenic variants in the gene for complement factor H | None |
ANA, antinuclear antibody; ANCA, antineutrophil cytoplasmic antibody; ESR, erythrocyte sedimentation rate; GBM, glomerular basement membrane; MPO, myeloperoxidase; PR3, proteinase 3.