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. 2016 Feb 1;6:19749. doi: 10.1038/srep19749

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(A) SBP increased significantly at week 12^th of HFD consumption. VNS significantly decreased SBP at week 16^th, week 20^th and week 24^th in obese-insulin resistance. (B) DBP increased significantly at week 20^th of HFD consumption. VNS significantly decreased DBP at week 16^th, week 20^th and week 24^th in obese-insulin resistance. (C) MAP increased significantly at week 20^th of HFD consumption. VNS significantly decreased MAP at week 16^th, week 20^th and week 24^th in obese-insulin resistance. Data were expressed as mean ± SEM. *p < 0.05 vs baseline, †p < 0.05 vs sham group, ‡p < 0.05 vs at 12 week after high-fat feeding of the same group, n = 8/group.