Skip to main content
. 2016 Feb 2;7:7. doi: 10.3389/fphar.2016.00007

FIGURE 3.

FIGURE 3

Effect of C. nutans extracts on TLR-4 activation in HEK-BlueTM-4 cells. (A) Cells treated with 100μg/mL of LP, LN, SP, SN failed to induce TLR-4 activation, while 100ng/mL of LPS induced significant TLR-4 activation (∗p < 0.05, one-way ANOVA post hoc Dunnett’s t-test) as compared to cells treated with 0.1% DMSO. (B) Cells were treated with various concentrations of extracts (1.5625–100 μg/mL) or 0.1% DMSO for 1 h followed by 18 h of LPS induction (100 ng/mL). Statistical significant difference from LPS induction are indicated as ∗p < 0.05 by one-way ANOVA post hoc Dunnet’s t-test. Each value represents means ± SD from three independent experiments.