Table 2. Anthropometric, clinical and biochemical parameters and adipsin levels of preeclamptic women.
| Variable | Preeclamptic women (n = 18) | P-value in the Friedman’s test* | P-value in the post-hoc analyses | ||||
|---|---|---|---|---|---|---|---|
| EP | MP | LP | EP Vs MP | EP Vs LP | MP Vs LP | ||
| Weight, Kg (mean ± SD) | 58.5 (+/− 6.7) | 65.6 (+/− 7.7) | 73.2 (+/− 8.5) | 0.00*** | 0.00*** | 0.00*** | 0.00*** |
| BMI, Kg/m2 (median (IQR)) | 23.14 (21.63–24.75) | 26.09 (24.06–28.04) | 29.74 (27.36–30.59) | 0.00*** | 0.00*** | 0.00*** | 0.00*** |
| Gestational age, weeks (median (IQR)) | 12.25 (11.6–12.58) | 24.3 (24.1–24.5) | 35.2 (34.28–35.58) | 0.00*** | 0.00*** | 0.00*** | 0.00*** |
| Systolic BP, mmHg (median (IQR)) | 108 (98.5–110) | 100 (100–110) | 104 (100–110) | 0.18 | — | — | — |
| Diastolic BP, mmHg (median (IQR)) | 65 (60–70) | 63 (60–68) | 60 (60–70) | 0.82 | — | — | — |
| Mean BP, mmHg (mean ± SD) | 78.2 (+/− 7.5) | 77.6 (+/− 5.6) | 77 (+/− 4) | 0.56 | — | — | — |
| Glucose, mg/dL(median (IQR)) | 80.5 (74.65–84) | 78.5 (70–81) | 70.6 (69–75) | 0.01** | 0.05* | 0.00** | 0.08 |
| Insulin, ng/mL (median (IQR)) | 11.5 (10.3–13.3) | 14.75 (11.05–18.32) | 13.5 (11.42–17.82) | 0.22 | — | — | — |
| HOMA-IR (median (IQR)) | 2.351 (1.889–2.508) | 2.946 (2.195–3.649) | 2.451 (2.116–3.348) | 0.27 | — | — | — |
| Total cholesterol, mg/dL (mean ± SD) | 182.2 (+/− 21.3) | 213 (+/− 33.6) | 237.7 (+/− 50.8) | 0.00*** | 0.00*** | 0.00*** | 0.06 |
| HDL-cholesterol, mg/dL (mean ± SD) | 50.1 (+/− 10.6) | 62.5 (+/− 14.8) | 55.4 (+/− 7.2) | 0.07 | — | — | — |
| LDL-cholesterol, mg/dL (mean ± SD) | 124.2 (+/− 40.5) | 145.1 (+/− 43.6) | 162 (+/− 70.7) | 0.01* | 0.01** | 0.02* | 0.21 |
| VLDL-cholesterol, mg/dL (median (IQR)) | 21.05 (16.23–26.48) | 32.8 (27.97–36.45) | 46.86 (32.12–62.19) | 0.00*** | 0.00*** | 0.00*** | 0.01** |
| Triglycerides, mg/dL (median (IQR)) | 105.2 (81.15–132.4) | 164 (139.8–182.2) | 243.7 (183.3–311) | 0.00*** | 0.00*** | 0.00*** | 0.00*** |
| Adipsin, ng/mL (mean ± SD) | 4764.4 (+/− 1414.4) | 3927.4 (+/− 674.8) | 5932.1 (+/− 2036.2) | 0.00** | 0.01** | 0.18 | 0.00*** |
| Leptin, pg/mL (mean ± SD) | 33734.14 (+/−11928.92) | 61060.55 (+/−23970.139) | 89780.93 (+/−41171.870) | 0.00*** | 0.00*** | 0.00*** | 0.027* |
Non-normally distributed data are listed as median (IQR). Normally distributed data are listed as mean ± SD. EP = early pregnancy, MP = middle pregnancy, LP = late pregnancy, PP = three months postpartum. HOMA (Homeostasis Model Assessment).