Figure 3.
Pharmacokinetic profile of dnCCL2 and dnCCL2-HSA chimera in vivo. Mice were intravenously injected with dnCCL2 (200 μg/kg) and dnCCL2-HSA chimera (200 μg/kg dnCCL2 equivalent), and the serum levels of each protein were determined at different time points. n = 3. Data are reported as ng/ml of dnCCL2 equivalent, the active part of the molecule, to allow direct comparison of the pharmacokinetic profiles.