Figure 4. Gene set overlap analysis.

The 19 reconstituted gene sets with P value<10⁻⁵ were considered. Their overlap was estimated by computing the pairwise Pearson correlation coefficient ρ between each pair of gene sets followed by discretization into one of three bins: 0.3≤ρ<0.5, low overlap; 0.5≤ρ<0.7, medium overlap; ρ⩾0.7, high overlap. Overlap is shown by edges between gene set nodes and edges representing overlap corresponding to ρ<0.3 are not shown. The network was drawn with Cytoscape⁴⁸.