Table 3.
The summary of NAB2‐STAT6 fusion patterns in intrathoracic solitary fibrous tumors
| Series | Cases | NAB2ex4‐STAT6ex2/3 | NAB2ex6‐STAT6ex16/17 | Others | Negative |
|---|---|---|---|---|---|
| Chmielecki et al. 6 | 5 | 5 (100%)a | 0 | 0 | 0 |
| Robinson et al. 7 | 8 | 3 (37.5%)b | 3 (37.5%) | 2 (NAB2ex7‐STAT6ex3) (25%) | 0 |
| Mohajeri et al. 8 | 8 | 7 (87.5%) | 0 | 0 | 1 (12.5%) |
| Barthelmeß et al. 9 | 27 | 25 (92.6%) | 0 | 1 (NAB2ex4‐STAT6ex18) (3.7%) | 1 (3.7%) |
| Vogels et al. 10 | 8 | 8 (100%) | 0 | 0 | 0 |
| Akaike et al. 11 | 24 | 18 (75%) | 0 | 3 (NAB2ex2‐STAT6ex6) (12.5%)2 (NAB2‐ex6‐STAT6ex18) (8.3%)1(NAB2ex2‐STAT6ex2) (4.2%) | 0 |
| Current study | 34 | 29 (85.3%) | 5 (14.7%) | 0 | 0 |
| Total | 114 | 95 (83%) | 8 (7%) | 9 (8%) | 2 (2%) |
a
The original paper reported NAB2 exon 4 fused to 5′‐UTR (5′‐untranslated region) of STAT6, which could be annotated to NAB2ex4‐STAT6ex2 based on the different gene reference.
b
Include a case with NAB2ex4‐STAT6ex5 fusion.