Table A1.

Overall and cause‐specific survival for advanced RCC and prostate cancer patients diagnosed in 2006–2010 versus those diagnosed in 2000–2003.^a

	Overall survival			Cause‐specific survival
	Hazard ratio	95% CI	P‐value	Hazard ratio	95% CI	P‐value
RCC (N = 11,336)	0.82	0.79–0.86	<0.001	0.80	0.76–0.84	<0.001
Prostate (N = 21,325)	0.95	0.91–0.99	0.006	0.94	0.90–0.98	0.003
z‐statisticb	5.41	na	<0.001	5.33	na	<0.001

RCC, renal cell carcinoma; CI, confidence interval.

^aHazard ratios for patients diagnosed in 2006–2010 relative to the reference category of patients diagnosed in 2000–2003 based on Cox regressions adjusting for age at diagnosis, sex, race, marital status, cancer grade, and dummy variables for having surgery on primary site, having radiation, and residence in states with laws requiring health plans to cover patient care costs in cancer clinical trials.

^b z‐statistic: (b1 – b2)/sqrt(se(b1)² + se(b2)²), where b1 is the coefficient for RCC, b2 is the coefficient for prostate, se(b1) is the standard error for b1, and se(b2) is the standard error for b2.