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. 2016 Feb 2;6:20353. doi: 10.1038/srep20353

Figure 7. Spatially and temporally resolved neuronal activity from hippocampal neurons growing on top of the MEOA.

Figure 7

Left: Confocal image of the neuronal dendrites (MAP2, top) and transduced neurons (mCherry, bottom) to depict the distribution of the neurons on the MEOA. Brightness and contrast are enhanced for visualization purposes. Right: Mapping of the latency to the first elicited spike (a) or the total spiking activity (b) during the stimulation ON period over 50 stimulation trials (0.2 Hz, 500 ms pulse train) show a clear temporal and spatial correlation to the stimulated optrode (colored in blue). Grey electrodes indicate sites that were not available for recording with the used system or broken contact.