Table 2.
Change of alleles and amino acids in the CDS region of MyD88 gene.
| Markers | ID | Position | Obs HET | Expt HET | Allele change | Amino acids change | Mutation |
|---|---|---|---|---|---|---|---|
| SNP1 | rs317890917 | 4810191 | 0.457 | 0.412 | C>T | 307 Leucine > phenylalanine | Nonsynonymous |
| SNP2 | rs14131328 | 4810253 | 0.258 | 0.349 | G>C | 327 Glutamine > Histidine | Nonsynonymous |
| SNP3 | rs14131329 | 4810257 | 0.405 | 0.419 | G>T | 329 Valine > Leucine | Nonsynonymous |
| SNP4 | rs14131330 | 4810266 | 0.481 | 0.481 | T>C | 332 Cysteine > Arginine | Nonsynonymous |
| SNP5 | rs14131331 | 4810276 | 0.436 | 0.483 | G>A | 335 Arginine > Histidine | Nonsynonymous |
| SNP6 | rs14131332 | 4810293 | 0.471 | 0.477 | G>C | 341 Glycine > Arginine | Nonsynonymous |
| SNP7 | rs14131333 | 4810352 | 0.474 | 0.483 | A>G | 360 Leucine > Leucine | Synonymous |
| SNP8 | G4810372T | 4810372 | 0.072 | 0.082 | G>T | 367 Serine > Isoleucine | Nonsynonymous |
Obs HET is observed heterozygosity; Expt HET is expected heterozygosity.