Table 3.
Allele frequency of mutation loci in the MyD88 gene.
| Markers | Alleles | χ 2, P value | OR | 95% CI | HWE (P) | MAF | |
|---|---|---|---|---|---|---|---|
| SNP1 (rs317890917) | T | C |
χ
2 = 4.604 P = 0.0319 |
0.6752 | 0.4712–0.9674 | 0.0873 | 0.29 |
| Cases | 170 (0.664) | 86 (0.336) | |||||
| Controls | 243 (0.745) | 83 (0.255) | |||||
|
| |||||||
| SNP3 (rs14131329) | T | G |
χ
2 = 2.384 P = 0.1226 |
0.7555 | 0.5290–1.079 | 0.6509 | 0.299 |
| Cases | 171 (0.668) | 85 (0.332) | |||||
| Controls | 237 (0.727) | 89 (0.273) | |||||
|
| |||||||
| SNP4 (rs14131330) | T | C |
χ
2 = 0.2487 P = 0.6180 |
1.0888 | 0.7794–1.521 | 1.0 | 0.402 |
| Cases | 156 (0.609) | 100 (0.391) | |||||
| Controls | 192 (0.589) | 134 (0.411) | |||||
|
| |||||||
| SNP5 (rs14131331) | G | A |
χ
2 = 0.3047 P = 0.5810 |
1.098 | 0.7869–1.534 | 0.122 | 0.407 |
| Cases | 155 (0.605) | 101 (0.395) | |||||
| Controls | 190 (0.583) | 136 (0.417) | |||||
|
| |||||||
| SNP6 (rs14131332) | G | C |
χ
2 = 0.0155 P = 0.9009 |
1.022 | 0.7306–1.4282 | 0.8877 | 0.393 |
| Cases | 156 (0.609) | 100 (0.391) | |||||
| Controls | 197 (0.604) | 129 (0.396) | |||||
|
| |||||||
| SNP7 (rs14131333) | G | A |
χ
2 = 0.3166 P = 0.5736 |
0.9089 | 0.6517–1.2677 | 0.8152 | 0.409 |
| Cases | 148 (0.578) | 108 (0.422) | |||||
| Controls | 196 (0.601) | 130 (0.399) | |||||
|
| |||||||
| SNP8 (G4810372T) | T | G |
χ
2 = 0.1708 P = 0.6794 |
0.8445 | 0.3786–1.884 | 0.1766 | 0.043 |
| Cases | 244 (0.953) | 12 (0.047) | |||||
| Controls | 313 (0.960) | 13 (0.040) | |||||
CI, confidence interval; OR, odds ratio; HWE (P), P value of the Hardy-Weinberg equilibrium test; and MAF, minimum allele frequency.