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. 2015 Dec 31;2016:6481862. doi: 10.1155/2016/6481862

Figure 5.

Figure 5

CPP induced by cocaine (1 mg/kg) in HNS and LNS adolescent mice pretreated 6 days before initiation of conditioning with vehicle (HNS, n = 15; LNS, n = 14), 0.1 mg/kg of WIN 55212-2 (HNS, n = 13; LNS, n = 12), or 1 mg/kg of rimonabant (HNS, n = 14; LNS, n = 13). Bars represent time in seconds spent in the drug-paired compartment during preconditioning (white), postconditioning (black), the last extinction session (light grey), and reinstatement (dark grey). Values are mean ± SEM. ∗∗ p < 0.01, difference with respect to the preconditioning session. ++ p < 0.01, difference with respect to the previous extinction session.