Table 1. Visual experience regulates the inhibitory CP for sensitivity to hearing loss.
sIPSC ampl. (pA) | sIPSC freq. (Hz) | sIPSC decay time (ms) | meIPSC ampl. (pA) | PPR | |
---|---|---|---|---|---|
Figure 1 | |||||
Ctrl (n=40) | −33.7±2.1 | 12.2±1.4 | 11.9±1.0 | −10.4±0.8 | 1.1±0.04 |
Normal, EP17 (n=21) | −26.3±1.7* | 8.5±0.8* | 20.4±2.5* | −7.8±0.3*** | 0.79±0.02*** |
Normal, EP18 (n=20) | −36.6±2.0 | 12.5±1.0 | 13.8±0.7 | −10.0±0.5 | 1.2±0.05 |
Figure 2 | |||||
Early, EP15 (n=12) | −20.0±1.8*** | 4.6±0.8*** | 24.5±3.0*** | −6.2±0.5*** | 0.78±0.03*** |
Early, EP16 (n=14) | −32.3±1.9 | 12.9±0.7 | 12.8±1.2 | −10.0±0.3 | 1.10±0.03 |
Early, EP16, DR (n=21) | −22.6±1.3*** | 8.3±0.6*** | 22.8±2.6*** | −7.0±0.7*** | 0.84±0.04*** |
Figure 3 | |||||
Delay, EP19 (n=15) | −23.7±3.2* | 6.15±0.8** | 27.2±3.7*** | −6.5±0.4*** | 0.84±0.02*** |
Delay, EP20 (n=14) | −18.9±1.4*** | 4.2±0.6*** | 19.7±1.7** | −6.2±0.3*** | 0.78±0.02*** |
Delay, EP21 (n=11) | −31.2±1.9 | 11.2±1.0 | 13.2±1.0 | −9.8±0.6 | 1.04±0.04 |
Delay, EP22 (n=22) | −34.9±2.9 | 12.7±1.6 | 12.0±1.2 | −10.0±0.3 | 1.19±0.07 |
Delay, no EP (n=22) | −31.1±3.2 | 14.5±1.2 | 13.9±1.2 | −11.7±0.3 | 0.98±0.05 |
CP, critical period; Delay, eyes open P23; DR, dark rear 14 to 17; Early, eyes open P14; EP, earplug insertion days; meIPSC, minimum evoked inhibitory postsynaptic current; Normal, eyes open P18; PPR, paired pulse ratio; sIPSC, spontaneous inhibitory postsynaptic current.
*P<0.05, **P<0.01 and ***P<0.001.