Table 2. Visual experience regulates the membrane property CP for sensitivity to hearing loss.
| RMP (mV) | AP Amp (mV) | AP thresh (mV) | Rin (MΩ) | τ (ms) | AP width (ms) | Sag (mV) | ΔmV | |
|---|---|---|---|---|---|---|---|---|
| Figure 1 | ||||||||
| Ctrl (n=57) | −64.5±0.4 | 97.1±1.0 | −31.3±0.6 | 127±6.1 | 9.6±0.4 | 1.01±0.04 | 1.30±0.6 | 1.88±0.07 |
| Normal, EP17 (n=19) | −64.1±0.5 | 95.5±1.3 | −30.9±0.9 | 114±10.3 | 12.1±1.1 | 1.06±0.3 | 0.7±0.0*** | 1.32±0.07*** |
| Normal, EP18 (n=24) | −66.3±0.8 | 100.0±1.9 | −34.7±2.3 | 125±12 | 9.4±0.7 | 0.90±0.06 | 1.33±0. 1 | 1.69±0.13 |
| Figure 2 | ||||||||
| Early, EP16 (n=26) | −65.7±0.5 | 98.7±1.3 | −31.6±1.1 | 112±10.1 | 10.1±0.6 | 0.93±0.4 | 1.37±0.06 | 1.86±0.12 |
| Early, EP16, DR (n=16) | −63.0±0.4 | 95.3±1.0 | −31.0±1.3 | 114±7.9 | 11.0±0.7 | 1.04±0.05 | 0.6±0.0*** | 1.28±0.07** |
| Delay, no EP (n=28) | −61.3±0.7** | 90.5±1.2*** | −27.6±1.4* | 132±10.7 | 12.0±0.9 | 1.10±0.07 | 1.26±0.08 | 1.98±0.11 |
AP amp, action potential amplitude; AP threshold, voltage threshold to spike; AP width, action potential depolarizing sag; CP, critical period; DR, dark rear; Delay, eyes opened P23; Early, eyes opened P14; EP, earplug insertion days; Normal, eyes opened P17; RMP, resting membrane potential; Rin, input resistance; τ, membrane time constant; ΔmV, change in membrane voltage per 10 pA step.
*P<0.05, **P<0.01 and ***P<0.001.