Table 3. Visual experience regulates the IPSC CP of recovery from hearing loss.
sIPSC ampl. (pA) | sIPSC freq. (Hz) | sIPSC decay time (ms) | meIPSC ampl. (pA) | PPR | |
---|---|---|---|---|---|
Figure 5 | |||||
Ctrl P35 (n=40) | −33.7±2.1 | 12.2±1.4 | 11.9±1.0 | −10.4±0.8 | 1.1±0.04 |
Normal, EP11–17 (n=25) | −47.5±3.2** | 16.3±0.9** | 8.7±0.5*** | −9.7±0.2 | 1.02±0.05 |
Normal, EP11–18 (n=15) | −24.6±2.4*** | 6.2±0.7*** | 18.3±1.2*** | −7.9±0.3*** | 0.81±0.02*** |
Early, EP11–17 (n=15) | −21.3±1.9*** | 6.7±0.9** | 20.2±3.6** | −7.3±0.5*** | 0.82±0.04*** |
Delay, EP11–18 (n=26) | −45.9±4.8** | 17.1±0.7*** | 7.7±0.4*** | −9.5±0.2 | 1.09±0.07 |
Figure 6 | |||||
Adult Ctrl, (n=21) | −39.4±2.1 | 11.8±0.9 | 9.5±0.6 | −11.2±0.4 | 1.03±0.02 |
Adult Normal, EP11–13 (n=15) | −36.4±3.3 | 12.6±0.9 | 10.2±0.8 | −10.7±0.8 | 1.00±0.06 |
Adult very early, EP11–13 (n=14) | −25.4±2.2*** | 8.1±0.6** | 19.0±2.1*** | −8.1±0.4*** | 0.77±0.02*** |
CP, critical period; Delay, eyes open P23; Early, eyes open P14; EP, earplug insertion days; meIPSC, minimum evoked inhibitory postsynaptic current; Normal, eyes open P18; PPR, paired pulse ratio; sIPSC, spontaneous inhibitory postsynaptic current; Very Early, eyes open P11.
*P<0.05, **P<0.01 and ***P<0.001.