Table 2.
Go terms of up-regulated and down-regulated miRNA target genes
| GO term | Up-regulated miRNA target genes | Down-regulated miRNA target genes | Normalized up-regulated miRNA target genes | Normalized down-regulated miRNA target genes |
|---|---|---|---|---|
| Biological adhesion | 17 | 9 | 1.07 % | 1.65 % |
| Biological regulation | 291 | 94 | 18.32 % | 17.28 % |
| Cellular component organization or biogenesis | 152 | 38 | 9.57 % | 6.99 % |
| Cellular process | 899 | 295 | 56.61 % | 54.23 % |
| Developmental process | 91 | 26 | 5.73 % | 4.78 % |
| Establishment of localization | 198 | 85 | 12.47 % | 15.63 % |
| Growth | 17 | 3 | 1.07 % | 0.55 % |
| Immune system process | 10 | 2 | 0.63 % | 0.37 % |
| Localization | 205 | 89 | 12.91 % | 16.36 % |
| Locomotion | 16 | 6 | 1.01 % | 1.10 % |
| Metabolic process | 875 | 266 | 55.10 % | 48.90 % |
| Multicellular organismal process | 106 | 34 | 6.68 % | 6.25 % |
| Multi-organism process | 5 | 2 | 0.31 % | 0.37 % |
| Negative regulation of biological process | 48 | 10 | 3.02 % | 1.84 % |
| Positive regulation of biological process | 31 | 10 | 1.95 % | 1.84 % |
| Regulation of biological process | 277 | 92 | 17.44 % | 16.91 % |
| Reproduction | 25 | 8 | 1.57 % | 1.47 % |
| Reproductive process | 21 | 6 | 1.32 % | 1.10 % |
| Response to stimulus | 205 | 73 | 12.91 % | 13.42 % |
| Rhythmic process | 3 | 1 | 0.19 % | 0.18 % |
| Signaling | 143 | 51 | 9.01 % | 9.38 % |
| Single-organism process | 471 | 171 | 29.66 % | 31.43 % |
| Cell | 615 | 198 | 38.73 % | 36.40 % |
| Cell junction | 17 | 12 | 1.07 % | 2.21 % |
| Cell part | 615 | 198 | 38.73 % | 36.40 % |
| Extracellular matrix | 7 | 3 | 0.44 % | 0.55 % |
| Extracellular matrix part | 4 | 2 | 0.25 % | 0.37 % |
| Extracellular region | 30 | 13 | 1.89 % | 2.39 % |
| Extracellular region part | 12 | 3 | 0.76 % | 0.55 % |
| Macromolecular complex | 294 | 85 | 18.51 % | 15.63 % |
| Membrane | 260 | 101 | 16.37 % | 18.57 % |
| Membrane-enclosed lumen | 104 | 23 | 6.55 % | 4.23 % |
| Membrane part | 171 | 71 | 10.77 % | 13.05 % |
| Organelle | 387 | 100 | 24.37 % | 18.38 % |
| Organelle part | 229 | 59 | 14.42 % | 10.85 % |
| Synapse | 12 | 11 | 0.76 % | 2.02 % |
| Synapse part | 10 | 9 | 0.63 % | 1.65 % |
| Virion | 1 | 1 | 0.06 % | 0.18 % |
| Virion part | 1 | 1 | 0.06 % | 0.18 % |
| Antioxidant activity | 5 | 0 | 0.31 % | 0 |
| Binding | 906 | 280 | 57.05 % | 51.47 % |
| Catalytic activity | 905 | 295 | 56.99 % | 54.23 % |
| Electron carrier activity | 29 | 10 | 1.83 % | 1.84 % |
| Enzyme regulator activity | 42 | 21 | 2.64 % | 3.86 % |
| Molecular transducer activity | 36 | 15 | 2.27 % | 2.76 % |
| Nucleic acid binding transcription factor activity | 20 | 6 | 1.26 % | 1.10 % |
| Protein binding transcription factor activity | 15 | 2 | 0.94 % | 0.37 % |
| Receptor activity | 27 | 12 | 1.70 % | 2.21 % |
| Structural molecule activity | 27 | 4 | 1.70 % | 0.74 % |
| Translation regulator activity | 1 | 0 | 0.06 % | 0 |
| Transporter activity | 81 | 48 | 5.10 % | 8.82 % |
| Channel regulator activity | 0 | 1 | 0 | 0.18 % |
| Metallochaperone activity | 0 | 1 | 0 | 0.18 % |