Table 3.
Hazard ratios of dropout per variables for variables that predicted dropout
| Unadjusted analysis | Adjusted analysis | |||
|---|---|---|---|---|
| Variable | HR (95 % CI) | P | AHRa (95 % CI) | P |
| Age | ||||
| 16–28 | 1.3 (1.2–1.5) | <0.001 | 1.4 (1.2–1.6) | 0.001 |
| 29–33 | 0.97 (0.83–1.1) | 0.722 | 1.0 (0.685–1.2) | 0.916 |
| 34–40 | 0.98 (0.84–1.1) | 0.769 | 0.95 (0.80–1.1) | 0.573 |
| 41–83 | Ref. | Ref | Ref. | - |
| Sex | ||||
| Female | Ref. | Ref. | - | |
| Male | 1.2 (1.1–1.4) | <0.001 | 1.4 (1.2–1.6) | <0.001 |
| Marital status | ||||
| Separated | 1.4 (1.2–1.7) | <0.001 | 1.3 (1.1–1.5) | 0.007 |
| Divorced | 1.4 (1.1–1.8) | 0.005 | 1.3 (1.1–1.7) | 0.017 |
| Widowed | 1.2 (0.90–1.3) | 0.515 | 1.1 (0.88–1.3) | 0.561 |
| Single | 1.6 (1.3–1.9) | <0.001 | 1.3 (1.1–1.6) | 0.012 |
| Married | Ref. | - | Ref. | - |
| Year of ART initiation | ||||
| 2008 | 1.8 (1.5–2.0) | <0.001 | 1.6 (1.4–1.9) | <0.001 |
| 2009 | 1.6 (1.4–1.9) | <0.001 | 1.4 (1.2–1.7) | <0.001 |
| 2010 | 1.2 (1.0–1.5) | 0.025 | 1.0 (0.82–1.2) | 0.963 |
| 2011 | Ref. | - | Ref. | - |
| Tuberculosis, history of | 1.6 (1.4–2.0) | <0.001 | 1.4 (1.2–1.7) | <0.001 |
| Kaposi’s sarcoma | 4.3 (3.3–5.7) | <0.001 | 3.3 (2.5–4.5) | <0.001 |
| Cryptococcosis, history of | 2.4 (1.7–3.4) | <0.001 | 2.2 (1.4–3.3) | <0.001 |
| Oral candidiasis | 1.3 (1.1–1.5) | <0.001 | - | - |
| Chronic diarrhea | 1.3 (1.2–1.6) | <0.001 | 1.3 (1.1–1.5) | 0.008 |
| Weight loss ≥10 % | 1.8 (1.6–2.1) | <0.001 | 1.5 (1.2–1.8) | <0.001 |
| HIV-associated dementia | 2.0 (1.2–12.8) | 0.008 | 2.6 (1.5–4.6) | 0.001 |
| CD4+ T cell count | ||||
| <100 (cells/μL) | 1.9 (1.5–2.4) | <0.001 | - | - |
| 100-199 | 1.2 (0.96–1.5) | 0.107 | - | - |
| 200-349 | 1.0 (0.83–1.3) | 0.768 | - | - |
| ≥350 | Ref. | - | - | - |
| Hemoglobin concentration | ||||
| ≤11.0 (g/dl) | 2.0 (1.7–2.4) | <0.001 | 1.9 (1.6–2.2) | <0.001 |
| 11.1–12.4 | 1.4 (1.2–1.6) | <0.001 | 1.4 (1.1–1.6) | 0.002 |
| 12.5–13.7 | 1.1 (0.91–1.3) | 0.411 | 1.1 (0.94–1.4) | 0.171 |
| ≥13.8 | Ref. | - | Ref. | - |
| Platelet counts | ||||
| ≤155 (cells/μL) | 1.2 (1.0–1.4) | 0.017 | - | - |
| 156–208 | 0.99 (0.84–1.2) | 0.865 | - | - |
| 209–267 | Ref. | - | - | - |
| 268–720 | 1.1 (0.93–1.3) | 0.301 | - | - |
| Total lymphocyte count | ||||
| ≤1.12 (x 103 cells/μL) | 1.6 (1.4–1.9) | <0.001 | 1.4 (1.2–1.7) | <0.001 |
| 1.13–1.6 | 1.3 (1.1–1.5) | 0.003 | 1.2 (1.0–1.4) | 0.048 |
| 1.61–2.0 | Ref. | - | Ref. | - |
| ≥2.01 | 1.3 (1.1–1.5) | 0.001 | 1.1 (0.94–1.4) | 0.171 |
HR hazard ratio, AHR adjusted hazard ratio, CI confidence interval
aFor the variables that remained in the final adjusted model