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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: J Am Coll Surg. 2015 Sep 15;221(6):1041–1049. doi: 10.1016/j.jamcollsurg.2015.09.005

Table 2.

Initial Recurrence after Resection of Perihilar Cholangiocarcinoma

Site No. of
recurrences		 All 177 patients with
a recurrence, %* 		All 306
patients, %
Local
  Liver hilum 34 19 11
  Hepaticojejunostomy 23 13 8
  Distal bile duct remnant 6 3 2
  Liver resection margin 23 13 8
Distant
  Liver intrahepatic 40 23 13
  Retroperitoneal lymph nodes† 42 24 14
  Peritoneum* 38 21 12
  Lung or mediastinum 25 14 8
  Abdominal wall/incision 8 5 2
  Bone 3 2 1
  Skin 1 1 0
  Adrenal gland 1 1 0
  Axillary or neck lymph nodes 2 1 1
  Spleen 1 1 0
Totals
  Recurrences, no. 245
  Patients with a recurrence, n 177 58
  Patients with an intial local recurrence, n 81 26
  Patients with an initial isolated local recurrence, n 54 18
  Patients with an initial distal recurrence, n 123 40

Note that patients can have an initial recurrence at more than one site. Consequently, total percentage of recurrence across all sites exceeds 100%.

*

Includes positive cytology of ascites and omental metastases.

†

Includes periaortic, pericaval, and celiac artery lymph nodes.