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Downregulation of genes in MSCs treated with 100 and 500 nM JQ1 for 24 hours. a qRT-PCR analysis of transcripts of cell cycle genes including CCNA2, CCNB2, CCND1, CDK1, CDK6, E2F2, c-MYC, and RB1. b DNA replication and mitosis genes including CDCA8, CENPF, NEK2, and TOP2A. *p ≤0.05. Ctrl control, JQ1 (S)-tert-butyl2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate
