Table 3.
Comparison of markers of carotid atherosclerosis (CIMT, sum of plaque thickness, and number of involved segments) in subjects with T2DM at the beginning of the study with regard to the rs2010963 and rs2071559 genotypes.
| rs2010963 | Mean (95% CI) | p | Linear trend analysis | |||
|---|---|---|---|---|---|---|
| CC (52) | CG (280) | GG (263) | F | p | ||
| CIMT (μm) | 1045 ± 192 (969–1121) |
996 ± 210 (964–1026) |
1026 ± 210 (995–1058) |
0.27 | 2.29 | 0.13 |
| Sum of plaque thickness (mm) | 7.58 ± 4.52 (5.67–9.49) |
7.79 ± 4.28 (7.09–8.48) |
8.11 ± 4.73 (7.35–8.88) |
0.76 | 0.009 | 0.93 |
| Number of involved segments | 2.67 ± 1.51 (2.07–3.26) |
2.48 ± 1.70 (2.24–2.73) |
2.54 ± 1.60 (2.31–2.77) |
0.84 | 0.34 | 0.56 |
|
| ||||||
| rs2071559 | Mean (95% CI) | p | Linear trend analysis | |||
| CC (131) | TC (309) | TT (155) | F | p | ||
|
| ||||||
| CIMT (μm) | 1053 ± 186 (1012–1092) |
1029 ± 200 (987–1070) |
988 ± 219 (958–1019) |
0.04 | 5.64 | 0.04 |
| Sum of plaque thickness (mm) | 8.81 ± 4.30 (7.83–9.78) |
8.27 ± 4.50 (7.26–9.29) |
7.31 ± 4.48 (6.61–8.00) |
0.03 | 5.91 | 0.02 |
| Number of involved segments | 2.87 ± 1.41 (0.94–1.65) |
2.38 ± 1.60 (0.95–1.73) |
2.24 ± 1.70 (0.98–1.46) |
0.64 | 0.22 | 0.83 |