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. 2016 Feb 1;11:16. doi: 10.1186/s13000-016-0468-4

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© Uehara et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Immunohistochemical profile of the present case. a: The NEC component shows marked CD10 expression, whereas WDEA does not. b: CD56 immunoreactivity is observed in the NEC component. c: ER expression is not detected in the NEC component, but strong ER expression is demonstrated in the WDEA component. d: Neither the NEC component nor the WDEA component exhibits CEA expression. e: p16 is not noted in the WDEA component. f: PTEN expression is weak but diffusely detected in the NEC component. g: Phosphorylated AKT is detected faintly in the NEC component