Table 3.

Clinical and pathological features of endometrial mixed carcinoma with NEC component in the lterature and in the present case

Case	Reference	Year	Age	Stage	Associated neoplasm	Treatment	Outcome
1	Tohya et al. [30]	1986	64	IIIb	Endometrioid adenosquamous carcinoma	Surgery	AWD	3 months
2	Tenti et al. [31]	1989	70	IVb	Endometrioid adenocarcinoma	Surgery, Chemotherapy, Hormonal therapy	DOD	2 years
3	Campo et al. [32]	1992	72	UK	Poorly differentiated adenocarcinoma	Radiotherapy	DOD	6 months
4	Huntsman et al. [2]	1994	72	IIa	Endometrioid adenocarcinoma	Surgery, Radiotherapy	AWD	13 months
5	Huntsman et al. [2]	1994	55	IV	Endometrioid adenocarcinoma	Radiotherapy, Chemotherapy	DOD	12 months
6	Huntsman et al. [2]	1994	54	IVb	Atypical complex hyperplasia	Surgery	DOD	12 months
7	Huntsman et al. [2]	1994	30	IVb	Atypical complex hyperplasia	Surgery	LFU
8	Huntsman et al. [2]	1994	37	IVb	Endometrioid adenocarcinoma	Surgery	LFU
9	Huntsman et al. [2]	1994	70	IIa	Endometrioid adenocarcinoma	Surgery	DOD	1 year
10	Huntsman et al. [2]	1994	62	IIIa	Endometrioid adenocarcinoma	Surgery	DOD	2 months
11	Huntsman et al. [2]	1994	59	Ic	Endometrioid adenocarcinoma	Surgery, Radiotherapy, Chemotherapy	DOD	4 years
12	Huntsman et al. [2]	1994	58	IVb	Endometrioid adenocarcinoma	Surgery	DOD	4 months
13	Huntsman et al. [2]	1994	53	IIb	Endometrioid adenocarcinoma	Surgery	NED	2 months
14	van Hoeven et al. [22]	1995	59	I	Adenocarcinoma	Surgery	AWD	2 years
15	van Hoeven et al. [22]	1995	62	I	Adenocarcinoma	Surgery	AWD	1.5 years
16	Sekiguchi et al. [33]	1998	60	Ib	Adenocarcinoma, Squamous cell carcinoma	Surgery	DOD	28 months
17	Katahira et al. [6]	2004	54	Ib	Endometrioid adenocarcinoma, Squamous	Surgery, Chemotherapy	NED	28 months
					cell carcinoma
18	Shaco-Levy et al. [34]	2004	79	UK	Papillary serous carcinoma	Surgery, Radiotherapy	DOD	5 months
19	Mulvany and Allen [5]	2007	80	Ic	Endometrioid adenocarcinoma	Surgery	DOD	5 months
20	Mulvany and Allen [5]	2007	77	IIb	Endometrioid adenocarcinoma	Surgery, Radiotherapy	DOD	23 months
21	Mulvany and Allen [5]	2007	79	IIIa	Endometrioid adenocarcinoma	Surgery, Radiotherapy	AWD	2 months
22	Mulvany and Allen [5]	2007	88	IIIc	Endometrioid adenocarcinoma	Surgery, Radiotherapy	AWD	1 month
23	Albores-Saavedra et al. [7]	2008	66	Ia	Endometrioid adenocarcinoma	Surgery	NED	4 years
24	Hwang et al. [35]	2010	59	Ic	Endometrioid adenocarcinoma, Squamous cell carcinoma	Surgery, Radiotherapy, Chemotherapy	NED	15 months
25	Sato et al. [8]	2010	56	IVb	Endometrioid adenocarcinoma	Surgery, Chemotherapy	DOD	3 years
26	Matsumoto et al. [9]	2011	44	IIIc	Atypical complex hyperplasia	Surgery, Radiotherapy, Chemotherapy	NED	4 years
27	Koo et al. [36]	2014	52	Ia	Endometrioid adenocarcnima, Atypical	Surgery, Chemotherapy	NED	15 months
					complex hyperplasia
28	Koo et al. [36]	2014	63	Ib	Endometrioid adenocarcnima, Atypical	Surgery, Chemotherapy	NED	5 months
					complex hyperplasia
29	Current report case	2015	33	II	Endometrioid adenocarcinoma	Surgery, Chemotherapy	NED	6 years

UK unknown, DOD dead on disease, AWD alive with disease, NED alive without evidence of disease, LFU lost to follow-up