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Effects of aCF-conditioned medium on action potential recordings of ESC-CMs. Representative AP waveforms of ESC-CM beating clusters cultured for 48 h in control medium (a) and aCF-conditioned medium (b). APD50 was prolonged (c). Maximal upstroke velocity (V max) was not significantly reduced (d). Data are expressed as mean ± SEM; ∗∗∗ p < 0.001.
