Table 1.
Univariate associations between antenatal factors and the risk of chronic lung disease (CLD). The right-most column provides the maximum number of infants with the attribute listed in each row; any differences are due to missing data. All other data are the percentage of infants with CLD among those infants with the attribute listed on the two left columns and the respiratory patterns listed as column headings. For example, among infants with a gestational age of 23–24 weeks who had the Low FiO2 respiratory pattern, the prevalence of CLD was 30%.
Antenatal factors | Respiratory Pattern | Row N |
|||
---|---|---|---|---|---|
Low FiO2 | PD* | EPPD* | |||
Gestational age (weeks) |
23–24 | 30 | 76 | 85 | 250 |
25–26 | 19 | 57 | 64 | 560 | |
27 | 15 | 33 | 62 | 394 | |
Birth weight (g) |
≤ 750 | 41 | 74 | 81 | 461 |
751–1000 | 14 | 43 | 58 | 512 | |
> 1000 | 11 | 29 | 51 | 231 | |
Birth weight Z-score |
< −2 | 70 | 68 | 86 | 75 |
≥ −2 to −1 | 38 | 70 | 80 | 163 | |
≥ −1 | 13 | 47 | 65 | 966 | |
Sex | Male | 18 | 56 | 69 | 638 |
Female | 16 | 47 | 69 | 566 | |
Antenatal steroid | Complete | 17 | 50 | 71 | 767 |
Partial | 16 | 56 | 67 | 316 | |
None | 21 | 53 | 64 | 117 | |
Number of fetuses | Single | 18 | 53 | 69 | 819 |
Multiple | 16 | 50 | 69 | 385 | |
Cesarean delivery | Yes | 16 | 54 | 70 | 804 |
No | 24 | 48 | 68 | 400 | |
Delivery indication | PTL | 15 | 49 | 67 | 526 |
pPROM* | 12 | 52 | 67 | 265 | |
Preeclampsia | 40 | 64 | 74 | 163 | |
Abruption | 19 | 48 | 73 | 126 | |
Cervical Insufficiency | 13 | 45 | 57 | 72 | |
Fetal indication | 10 | 67 | 85 | 52 | |
Percent CLD | 17 | 52 | 69 | 52 | |
Maximum Column N | 240 | 456 | 508 | 1204 |
PD=pulmonary deterioration, EPPD=early and persistent lung dysfunction, pPROM=prolonged, premature rupture of membranes