Table 3.

Univariate associations between late neonatal factors and the risk of chronic lung disease (CLD). The right-most column provides the maximum number of infants with the attribute listed in each row; any differences are due to missing data. All other data are the percentage of infants with CLD among those infants with the attribute listed on the two left columns and the respiratory patterns listed as column headings. For example, among infants who received hydrocortisone that had the Low FiO2 respiratory pattern, the prevalence of CLD was 40%.

Late neonatal factors		Respiratory Pattern			Row N
		Low FiO2	PD*	EPPD*
Hydrocortisone	Yes	40	76	69	142
	No	17	40	69	1062
Dexamethasone	Yes	50	74	86	78
	No	17	51	67	1126
Analgesic	Yes	27	66	75	578
	No	14	39	60	626
Sedation	Yes	32	63	74	264
	No	16	49	67	940
Vitamin A	Yes	21	50	65	354
	No	16	52	72	850
Confirmed bacteremia	Yes	16	63	73	298
	No	17	48	68	905
Confirmed tracheal infection	Yes	28	63	74	230
	No	17	49	68	964
Mechanical ventilation(day 14)**	Yes	31	72	77	717
	No	14	26	36	486
Mechanical ventilation(day 21)**	Yes	43	72	77	696
	No	12	27	39	504
Patent ductus arteriosus (PDA)	Yes	20	58	71	798
	No	14	40	64	406
Pneumothorax (PTX)	Yes	25	73	81	91
	No	17	50	68	1113
Pulmonary interstitial emphysema (PIE)	Yes	50	79	85	189
	No	16	49	63	1015
Necrotizing Enterocolitis***	No/Stage I, II	15	50	69	1009
	Stage IIIa	100	67	50	13
	Stage IIIb	38	92	68	48
	Isolated perf	50	71	88	34
Percent CLD		17	52	69	52
Maximum Column N		240	456	508	1204

^*PD=pulmonary deterioration, EPPD=early and persistent pulmonary dysfunction

^**Includes conventional mechanical ventilation and high frequency ventilation

^***Bell's staging