Table 3.
Comparison of laboratory data between patients with severe leptospirosis admitted to ICU and wards
| Parameters | ICU | Non-ICU | p |
|---|---|---|---|
| N = 83 | N = 123 | ||
| Creatinine (mg/dl) | 3.97 ± 2.25 | 2.97 ± 2.4 | 0.004 |
| Urea (mg/dl) | 131.8 ± 68 | 101.2 ± 72.5 | 0.004 |
| Potassium (mEq/L) | 3.91 ± 0.85 | 3.9 ± 1.07 | 0.951 |
| Sodium (mEq/L) | 133 ± 6.61 | 130 ± 19 | 0.317 |
| AST (UI/L) | 169.8 ± 199 | 132.13 ± 183 | 0.285 |
| ALT (UI/L) | 101.83 ± 90 | 101.90 ± 153 | 0.998 |
| LDH (UI/L) | 810.25 ± 539 | 671.94 ± 420 | 0.416 |
| Total bilirubin (mg/dl) | 15 ± 12.2 | 8.6 ± 9.5 | 0.001 |
| Direct bilirubin (mg/dl) | 9.2 ± 8.5 | 5.9 ± 7.11 | 0.018 |
| Indirect bilirubin (mg/dl) | 4.48 ± 6.08 | 2.38 ± 3.22 | 0.013 |
| Hematocrit (%) | 29.6 ± 6.4 | 33.1 ± 8.63 | 0.003 |
| Hemoglobin (g/dl) | 10.2 ± 2.4 | 11.6 ± 1.95 | <0.001 |
| WBC (103/mm3) | 14.30 ± 7.70 | 14.95 ± 1.82 | 0.772 |
| Platelets (103/mm3) | 94.42 ± 86.74 | 128.89 ± 137.01 | 0.035 |
| pO2 (mmHg) | 87.3 ± 32 | 83 ± 34 | 0.542 |
| pCO2 (mmHg) | 31.81 ± 9.4 | 32.64 ± 8.5 | 0.636 |
| pH | 7.35 ± 0.08 | 7.36 ± 0.07 | 0.127 |
| Bicarbonate (mEq/L) | 17.89 ± 4.82 | 18.8 ± 4.89 | 0.330 |
| SaO2 (%) | 93.82 ± 5.7 | 91.6 ± 10.17 | 0.190 |
AST aspartate aminotransferase, ALT alanine aminotransferase, LDH lactate dehydrogenase, WBC white blood cells, PO 2 O2 partial pressure, PCO 2 PCO2 partial pressure, SaO 2 O2 saturation
Chi-squared test, T-Student test and Mann–Whitney test were used to perform this comparison. Values expressed as mean ± SD and percentage. P values ≤ 0.05 were considered statistically significant