Table 2.
Secretion of major neurotrophic and support factors by MSCs from different tissue sources.
| BDNF | bFGF | GDNF | IGF | NGF | NT-3 | NT-4/5 | VEGF | |
|---|---|---|---|---|---|---|---|---|
| AF | • | ° | • | • | • | • | • | • |
| AT | • | ° | ° | • | • | • | • | • |
| BM | • | ° | • | • | ° | • | • | • |
| DP | • | • | • | • | • | • | • | • |
| UC | • | • | • | — | • | • | • | • |
AF (amniotic fluid), AT (adipose tissue), BM (bone marrow), DP (dental pulp), and UC (umbilical cord tissue) derived MSCs; •: detected in cell culture supernatant/conditioned medium; °: conflicting reports on the detection of the specific factor in cell culture supernatant/conditioned medium; —: not disclosed in presented literature; and references: [38, 70, 71, 74, 78, 96, 97, 103, 111, 131–136].