Table 5.
Average rank (Mann-Whitney test) of continuous variables evaluated in relation to the SNP alleles (n = 120).
| SNP | Parameter | n | Average Rank | p |
|---|---|---|---|---|
| Leptin | ||||
|
| ||||
| HTR2C rs3813929 (both genders) | Hemi/homozygous | 115 | 59.17 | 0.044 |
| Heterozygotes | 5 | 91.20 | ||
|
| ||||
| HTR2C rs3813929 (females) | Heterozygotes | 5 | 9.10 | 0.704 |
| Homozygous | 17 | 12.21 | ||
|
| ||||
| HTR2C rs3813929 (males) | Hemizygous C | 85 | 48.16 | 0.232 |
| Hemizygous T | 13 | 58.27 | ||
|
| ||||
| LEPR | Presence of allele A | 93 | 57.04 | 0.043 |
| Absence of allele A | 27 | 72.41 | ||
|
| ||||
| ALT | ||||
|
| ||||
| LEP | Absence of allele G | 16 | 44.84 | 0.053 |
| Presence of allele G | 104 | 62.91 | ||
|
| ||||
| CYP2D6 | Absence of allele C | 113 | 58.60 | 0.016 |
| Presence of allele C | 7 | 91.14 | ||
|
| ||||
| HOMA-IR | ||||
|
| ||||
| MC4R | Absence of allele T | 7 | 35.14 | 0.047 |
| Presence of allele T | 113 | 62.07 | ||
|
| ||||
| CYP2D6 | Heterozygotes | 36 | 56.38 | 0.032 |
| Homozygous | 84 | 62.27 | ||