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. 2016 Feb 2;15:10. doi: 10.1186/s12943-016-0495-5

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© Schrödter et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — The expression of 14 target mRNAs in renal cell carcinoma (red bars) and normal renal (green bars) tissue was validated using quantitative real-time PCR; the expression levels were normalized using ACTB and TBP as reference genes. Significant overexpression of SLC6A3, NPTX2, TFAIP6, NDUFA4L2, ENPP3, FABP6 and SPINK13 mRNA in renal cell carcinoma was confirmed, whereas FXYD4, SLC12A1, KNG1, NPHS2, SLC13A3, GCGR and PLG mRNA levels were downregulated (all p < 0.001)