Fig. 4.

Phylogenetic analysis of eukaryotic bZIPs. Unrooted Maximum Likelihood tree of bZIPs from two species representing each of the five main eukaryotic lineages: metazoans (blue); fungi (green); amoebozoans (red); plants (brown); and heterokonts (black). To avoid crowding the tree, the Arabidopsis bZIP set was restricted to two genes from each bZIP family (as described in [10]). Branches are collapsed into kingdom-specific clades and the name is indicated when possible. Statistical support was obtained with 1000 bootstrap replicates and an asterisk indicates well-supported branches (>50 %). A unique cluster containing orthologues from the metazoan OASIS-ATF6 family, the fungal HAC1 family and the plant group proto-B group is highlighted in yellow. bZIPs from this clade share five additional conserved positions, indicated by white circles (top logo, yellow background), compared to the whole eukaryotic set (bottom logo). Black circles indicate five highly conserved positions of the bZIP domain discussed earlier