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. 2016 Feb 2;14:6. doi: 10.1186/s12958-016-0140-6

Table 2.

Meta-analysis results for the two studied polymorphisms and RPL risk

Gene polymorphism Inherited model Heterogeneity-test Analysis modela Pooled OR (95% CI) P
P for Q test I 2 (%)
-238G/A Codominant (A vs. G) 0.001 80.7 REM 0.996 [0.932,1.065] 0.912
Homozygous (AA vs. GG) 0.017 70.7 REM 0.830 [0.238, 2.887] 0.769
Heterozygous (AA vs. GA) 0.175 39.5 FEM 0.888 [0.54, 1.46] 0.640
Dominant(AA+GA vs. GG) 0.007 75.2 REM 0.908 [ 0.566, 1.456] 0.690
Recessive(AA vs. GA+GG) 0.036 64.9 REM 1.212 [ 0.394, 3.729] 0.737
-308G/A Codominant (A vs. G) 0.017 63.6 REM 0.737 [0.539, 1.01] 0.057
Homozygous (AA vs. GG) 0.713 0 FEM 0.445 [0.268, 0.741] 0.002
Heterozygous (AA vs. GA) 0.658 0 FEM 0.519 [0.303, 0.89] 0.017
Dominant(AA+GA vs. GG) 0.018 54.8 REM 0.836 [0.622, 1.124] 0.236
Recessive(AA vs. GA+GG) 0.774 0 FEM 2.141 [1.291, 3.55] 0.003