Fig. 2.

Radiographic progression over 5 years according to Simplified Disease Activity Index (SDAI) remission and 14-3-3η positivity. Generalized linear model analysis was performed to compare radiographic progression over time with 14-3-3η ≥0.50 ng/ml. a Relative to patients with lower 14-3-3η levels, erosive damage progression (ΔErosion) was significantly higher in patients with 14-3-3η ≥0.50 ng/ml at 18 months, whether the patients were in SDAI remission (p = 0.002) or had active SDAI levels at 18 months (p <0.001). b Relative to patients with lower 14-3-3η levels, yearly erosive damage progression (ΔErosion) was significantly higher in patients with 14-3-3η ≥0.50 ng/ml at the previous visit, whether the patients were already in SDAI remission (p = 0.0079) or had active SDAI levels (p <0.001) at the previous visit. SEM standard error of the mean