Table 3.
Characterisation of clonal complexes and comparison of alpha toxin production rates
| Clonal complex | ST (n) | spa (n) | agr (n) | Superantigensb | Production (m/sd)d α toxin |
|---|---|---|---|---|---|
| CC5 | ST5 (3) | t071, t548, t002 | II (3) | selp (2), egc (3), selw (3), selx (3) | 1.1 (+/−0.7) |
| ST1457 (1) | t067 | II | tst, selp, egc, selw, selx | ||
| CC6 | ST6 (1) | t3802 | I | sea, selx | |
| ST7 | ST7 (3) | t091 (3) | I (3) | selp (3), selx (3) | 1.32 (+/−0.55) |
| CC8 | ST8 (4) | t3308, t024, t008, t648 | I (5) | sea (1), selx (4) | 8.78 (+/−10.23) |
| ST3275 (1)a | t008 | sea (1), selx (1) | |||
| ST630 (1) | t377 | IV | selx | ||
| CC10 | ST10 (1) | t6873 | II | seb, seh, egc, selx | |
| CC15 | ST15 (2) | t2453, t084 | II (5) | selx (2) | 0.42 (+/−0.55) |
| ST582 (3) | t084 (3) | selx (3) | |||
| CC22 | ST22 (3) | t790, t13078, t005 | I (3) | sec (1), sell (1), egc (3), selx (3) | 15.93 (+/−18.43) |
| CC25 | ST25 (1) | t3232 | I | egc, selx | |
| CC30 | ST30 (10) | t433 (2), t4401, t11980, t617, t012, t021 (2), t342 (2) | III (10) | tst (5), sea (5), egc (10), selx (10) | ≤0.01 |
| ST34 (2) | t3805, t15407 | III (2) | tst (2), seh (2), egc (2), selx (2) | ||
| CC45 | ST45 (8) | t015 (2), t333, t230, t583, t065, t350, t553 | I (8) | sec (5), sell (5), egc (8), selx (8)c | 4.69 (+/−2.36) |
| CC50 | ST50 (2) | t246 (2) | IV (2) | egc (2), selx (2) | |
| CC51 | ST121 (2) | t284, t1441 | IV (2) | egc (2), selx (2) | |
| CC101 | ST101 (2) | t056 (2) | I (2) | selx (2) | |
| CC779 | ST779 (1) | t878 | III | sed, sej, selr, selx |
aStrain 767 N-10 displayed a different allele of aroE, being a new single locus variant of ST8
bAll superantigen genes were included with the exception of pseudogenes
cSuperantigen-like gene selx including frameshift nonsense mutation (I11)
dMean (m) and standard deviation (sd) of production rates were determined of CC groups comprising one or more STs (number of strains n ≥ 3)