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. Author manuscript; available in PMC: 2016 Feb 2.
Published in final edited form as: Nutr Cancer. 2015;67(7):1104–1112. doi: 10.1080/01635581.2015.1075560

Table 3.

Changes in expression of proliferation (MCM-2) and cell cycle inhibition (p27) biomarkers in benign prostate tissue following random assignment to lycopene-rich tomato extract or placebo capsules

Lycopene
 Placebo
Biomarker Pre-Rx Post-Rx Mean Δ
(95% CI)		 Pre-Rx Post-Rx Mean Δ
(95% CI)
MCM-2, % positive
epithelial cells		 7.58 8.24 0.66
(−1.08-2.40)		 8.45 8.74 0.29
(−1.51 -2.08)
MCM-2, H-Score (%
positive × intensity)		 0.12 0.13 0.01
(−0.02-0.04)		 0.13 0.14 0.01
(−0.02-0.04)
p27, % positive
epithelial nuclei		 52.96 52.01 −0.95
(−8.16-6.27)		 56.34 54.71 −1.63
(−9.75-6.50)
p27, H-Score(%
positive × intensity)		 1.00 0.98 −0.02
(−0.21-0.17)		 1.10 1.03 −0.07
(−0.26-0.12)