WT(WTbm) and WT(ARKObm) mice did not exhibit differences in body weight over the course of the feeding period (A) nor differences in tissue weight at study termination (B). Greater accumulation of visceral and total fat was observed among WT(ARKObm) mice on a chow diet (C) and after 8 weeks of high-fat feeding (D) but not after 16 weeks of high-fat feeding (E). Livers from WT(ARKObm) mice had higher triglyceride and cholesterol content (F). *p < 0.05, **p < 0.01, ***p < 0.001. WT, wild-type; WTbm, WT bone marrow; ARKObm, androgen receptor knockout bone marrow.