Table 3.
Compound | Method of flow cytometry (reduced 2′,7′-dichlorofluorescein diacetate (DCFH-DA) oxidation by ROS) |
---|---|
Activity rank order (ARO = I for the highest activity; ARO = III for the mindest activity) (Effective [IC]: 1; 5; 10; 50 μM) | |
Lacidipine | + + + (ARO = I) |
Lercanidipine | + + (ARO = II) |
Amlodipine | No effect |
Nifedipine | No effect |
Nimodipine | No effect |
Verapamil | + (ARO = III) |
α-Tocopherol | + + + (ARO = I) |