Table 2.
Comparisons of the minor allele frequencies of the four SNPs and examinations of the Hardy-Weinberg equilibrium among the entire cohort.
| SNPs | rs # | Nucleotide Change (amino acid change) | Location | Controls (n = 780) | Cases (n = 671) | ||
|---|---|---|---|---|---|---|---|
| MAF | HWE p value | MAF | HWE p value | ||||
| SOD2 | rs4880 | T → C (Val → Ala) |
exon 2 | 13.97% | 0.768 | 17.36% | 0.423 |
| GPX1 | rs1050450 | C → T (Pro → Leu) |
exon 2 | 5.38% | 0.720 | 5.29% | 0.249 |
| P12A | rs1801282 | C → G (Pro → Ala) |
exon B | 3.08% | 0.526 | 4.99% | 0.020 |
| C161T | rs3856806 | C → T (His → His) |
exon 6 | 24.29% | 0.697 | 26.53% | 0.488 |
HWE = Hardy-Weinberg equilibrium.
MAF = minor allele frequency.