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. 2015 Nov 12;12:79–86. doi: 10.2142/biophysico.12.0_79

Figure 3.

Figure 3

Urinary adiponectin levels measured by our ultrasensitive ELISA for healthy subjects and DM patients. (A) The urinary adiponectin concentrations in DM patients (DM, N=3) were higher (P<0.05) than those in healthy subjects (ND, N=6). DM-N, a DM patient with nephropathy; M, male; F, female. (B) The urinary creatinine concentrations in DM patients (N=3) were lower (P<0.05) than those in healthy subjects (N=6). (C) The urinary adiponectin levels, which were the values of adiponectin concentrations corrected by creatinine concentrations, were 0.73±0.50 (ng/mg creatinine) for heathy subjects (N=6) versus 12.02±3.85 ng/mg creatinine for DM patients (N=3). That is, the urinary adiponectin levels were higher in DM patients than in healthy subjects, and there seemed to be a threshold adiponectin level at around 4 ng/mg creatinine between healthy subjects and DM patients. The worse the progression of DM, the higher the urinary adiponectin level became.