Table 2.
Items | Patients, n | Events, n | OS (univariate) Hazard radio (95% CI) | P |
---|---|---|---|---|
All patients | 76 | 32 | ||
Age* | 0.410 | |||
≤65 years | 38 | 13 | 1.000 (reference) | |
>65 years | 38 | 19 | 1.348 (0.662–2.746) | |
Gender | 0.290 | |||
Female | 53 | 20 | 1.000 (reference) | |
Male | 23 | 12 | 0.679 (0.332–1.390) | |
Localization | 0.074 | |||
Proximal + middle | 47 | 23 | 1.000 (reference) | |
Distal | 29 | 9 | 0.490 (0.223–1.073) | |
Differentiation | 0.052 | |||
Well + moderately | 31 | 9 | 1.000 (reference) | |
Poorly | 45 | 23 | 2.152 (0.993–4.664) | |
Lauren classification | 0.792 | |||
Intestinal type | 57 | 25 | 1.000 (reference) | |
Diffuse-type | 19 | 7 | 1.086 (0.589–1.999) | |
T stage | 0.027 | |||
T1 + T2 | 13 | 1 | 1.000 (reference) | |
T3 + T4 | 63 | 31 | 3.096 (1.140–8.409) | |
N stage | 0.012 | |||
N0 + N1 | 33 | 9 | 1.000 (reference) | |
N2 + N3 | 43 | 23 | 2.690 (1.239–5.840) | |
TNM stage | 0.015 | |||
I + II | 29 | 8 | 1.000 (reference) | |
III | 47 | 24 | 1.655 (1.101–2.487) | |
Tumor size* | 0.078 | |||
<3.5 cm | 40 | 12 | 1.000 (reference) | |
≥3.5 cm | 36 | 20 | 1.906 (0.931–3.902) | |
miR-34a expression | 0.018 | |||
High | 40 | 10 | 1.000 (reference) | |
Low | 36 | 22 | 2.469 (1.166–5.228) |
*Split at median. OS: Overall survival; 95% CI: 95% confidence interval.