Table 1.
Clinical features of 120 Chinese PAP patients
| Characteristics | n | Baseline |
|---|---|---|
| Age (year, mean ± SD) | 120 | 43 ± 11 |
| Pulmonary function test (%, mean ± SD) | ||
| FVC%Pred | 92 | 77.3 ± 18.4 |
| FEV1%Pred | 92 | 76.8 ± 17.5 |
| FEV1/FVC%Pred | 92 | 85.8 ± 9.4 |
| DLCO%Pred | 92 | 57.2 ± 19.6 |
| TLC%Pred | 92 | 79.0 ± 12.0 |
| 6-min walk test (m, mean ± SD) | 81 | 490.9 ± 131.5 |
| Arterial blood gas | ||
| PaO2 (mmHg, mean ± SD) | 106 | 64.5 ± 13.8 |
| PA-aO2 (mmHg, median) | 106 | 41.4 (32.6–54.2)* |
| Shunt fraction rate (mean ± SD) | 106 | 21.2 ± 13.0 |
| Serum biochemical markers | ||
| LDH (IU/L, median) | 99 | 269 (213–390)* |
| CEA (ng/ml, median) | 82 | 6.8 (4.4–15.0)* |
| NSE (ng/ml, mean ± SD) | 89 | 12.6 ± 7.1 |
| TC (mmol/L, mean ± SD) | 93 | 5.3 ± 1.3 |
| TG (mmol/L, median) | 93 | 1.8 (1.3–2.4) |
*Range. SD: Standard deviation; PAP: Pulmonary alveolar proteinosis; %Pred: Percentage of the predicted value; FVC: Forced vital capacity; FEV1: Forced expiratory volume in one second; DLCO: Diffusing capacity of the lung for carbon monoxide; TLC: Total lung capacity; PaO2: Partial pressure of oxygen in arterial blood; PA-aO2: Alveolar-arterial oxygen gradient; LDH: Lactate dehydrogenase; CEA: Carcinoembryonic antigen; NSE: Neuron-specific enolase; TC: Cholesterol; TG: Triglyceride. 1 mmHg = 0.133 KPa.